The Synthesis of (±)-Ochrobirine. A New Route to the Spirobenzylisoquinoline System
| Autor: | D. B. MacLean, N. E. Cundasawmy |
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| Rok vydání: | 1972 |
| Předmět: | |
| Zdroj: | Canadian Journal of Chemistry. 50:3028-3036 |
| ISSN: | 1480-3291 0008-4042 |
| DOI: | 10.1139/v72-481 |
| Popis: | The spirobenzylisoquinoline system has been synthesized from substituted 2-phenyl-1,3-indandiones as starting materials. Ring B of the spiro system was constructed by a modified Pomeranz–Fritsch reaction. The reaction sequence has been applied to the synthesis of an analog of ochrobirine and then to (±)-ochrobirine itself. |
| Databáze: | OpenAIRE |
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