Degeneration of retinal nerve fiber layer in patients with multiple sclerosis. Prospective study with three years follow‐up
| Autor: | E Garcia Martin, E Sancho Moro, R Herrero Latorre, Maria Satue, J Fernandez Tirado |
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| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Visual acuity genetic structures medicine.diagnostic_test business.industry Multiple sclerosis Nerve fiber layer Retinal General Medicine medicine.disease eye diseases Visual field Surgery Ophthalmology chemistry.chemical_compound medicine.anatomical_structure Optical coherence tomography chemistry medicine Optic nerve sense organs medicine.symptom business Snellen chart |
| Zdroj: | Acta Ophthalmologica. 89 |
| ISSN: | 1755-3768 1755-375X |
| DOI: | 10.1111/j.1755-3768.2011.312.x |
| Popis: | Purpose To quantify changes over three years in the retinal nerve fiber layer (RNFL) of patients with multiple sclerosis (MS) and to evaluate if treatments are a protector factor of CFNR degeneration. Methods One hundred and eighty-eight eyes of 94 MS patients were followed-up during 3 years. All patients underwent a complete ophthalmic examination that included assessment of visual acuity (Snellen chart), colour vision (Ishihara pseudoisochromatic plates), visual field examination, optical coherence tomography (OCT) and visual evoked potentials (VEP). All patients were re-evaluated in a period of 12, 24 and 36 months in order to quantify the changes in the retinal nerve fiber layer (RNFL). Results Changes were obtained in the RNFL thickness with a 36-month follow-up. There were significant decreases (P |
| Databáze: | OpenAIRE |
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