Patient-derived Fab structures suggest mechanism by which affinity maturation promotes autoantibody recognition of MuSK in the autoimmune disease myasthenia gravis

Autor:	Kevin C. O’Connor, Rachel L. Redler, Steven J. Burden, Damian C. Ekiert, Casey Vieni, Miriam L. Fichtner, Ljuvica Kolich
Rok vydání:	2020
Předmět:	Autoimmune disease Chemistry Mechanism (biology) Autoantibody Condensed Matter Physics medicine.disease Biochemistry Myasthenia gravis Inorganic Chemistry Affinity maturation Structural Biology Immunology medicine General Materials Science Physical and Theoretical Chemistry
Zdroj:	Acta Crystallographica Section A Foundations and Advances. 76:a106-a106
ISSN:	2053-2733
DOI:	10.1107/s0108767320098931
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3bdbd816bb950a588f6d5397dfa1a4b3 https://doi.org/10.1107/s0108767320098931 Zobrazit plný text záznamu Plný text