Prevalence and prognostic implications of the no-reflow phenomenon in patients undergoing primary percutaneous coronary intervention in a university center in a middle-income country

Autor: L B Godinez Cordova, H Gonzalez-Pacheco, R Gopar-Nieto, G Eid-Lidt, J L Briseno-De La Cruz, D Araiza-Garaygordobil, S Mendoza-Garcia, A Altamirano-Castillo, H Ontiveros-Mercado, A Arias-Mendoza
Rok vydání: 2022
Předmět:
Zdroj: European Heart Journal. 43
ISSN: 1522-9645
0195-668X
DOI: 10.1093/eurheartj/ehac544.2066
Popis: Background No-reflow (TIMI flow ≤2) during primary PCI for STEMI occurs in 7–25% of cases, indicates poor myocardial tissue perfusion, and is associated with a poor outcome. (1–3) The incidence in our hospital is unknow. Purpose To analyse the prevalence of no-reflow and the 30-day mortality in our hospital. Methods We analysed the database of a teaching hospital and identified 2463 patients who underwent primary PCI from January 2006 to December 2021. No-reflow was defined as post-PCI TIMI flow ≤2, in the absence of post-procedural significant (≥25%) residual stenosis, abrupt vessel closure, dissection, perforation, thrombus of the original target lesion, or epicardial spasm. The outcome measure was 30-day mortality. Results Of total of 2050 patients, no-reflow phenomenon was found in 413 (16.8%) patients, and it was associated with significantly higher 30-day mortality (16.7% vs. 4.29%; p = 1 (37% vs. 26.4%; p = Conclusion No-reflow occurred in 16.8% of STEMI patients undergoing primary PCI and was more likely with older age, delayed presentation, anterior myocardial infarction and Killip class >1. No-reflow was associated with a higher mortality at 30-day follow-up. Funding Acknowledgement Type of funding sources: None.
Databáze: OpenAIRE