Campylobacter pylori and Its Role in Peptic Ulcer Disease
| Autor: | E.A.J. Rauws, G.N.J. Tytgat |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
Duodenal cap business.industry Campylobacter digestive oral and skin physiology Gastroenterology Inflammation macromolecular substances bacterial infections and mycoses medicine.disease_cause medicine.disease digestive system diseases Pathogenesis Duodenitis Internal medicine Metaplasia Concomitant medicine Gastritis medicine.symptom business |
| Zdroj: | Gastroenterology Clinics of North America. 19:183-196 |
| ISSN: | 0889-8553 |
| Popis: | In almost all patients with genuine nondrug-induced duodenal or gastric ulcer there is evidence of gastric Campylobacter pylori colonization and concomitant inflammation. C. pylori is only demonstrable in the duodenal cap when there is "gastric mucus metaplasia." Suppression or eradication of C. pylori with antibiotic therapy may accelerate duodenal ulcer healing. The relapse rate of duodenal ulcer is less after temporary clearing or permanent eradication of C. pylori. As eradication of C. pylori reduces or eliminates gastric (and duodenal) inflammation, this renders the gastroduodenal mucosa less susceptible to reulceration. Interference with C. pylori status presumably explains the retardation of relapse of duodenal ulcer healing with colloidal bismuth subcitrate. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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