Nitrogen metabolism during the oral andparenteral administration of the amino acids of hydrolyzed casein

Autor: Allan M. Butler, Alfred T. Shohl, Kenneth D. Blackfan, E.A. MacLachlan
Rok vydání: 1939
Předmět:
Zdroj: The Journal of Pediatrics. 15:469-475
ISSN: 0022-3476
DOI: 10.1016/s0022-3476(39)80001-4
Popis: Summary Hydrolyzed casein, consisting largely of amino acids, was givenorally to infants as the sole source of nitrogen. The amino acids, in the presence of the non-nitrogenous dietary essentials, gave positive nitrogen balances in all cases. It was also found that positive and sufficient nitrogen balances wereobtained by the intravenous administration of hydrolyzed casein together with glucose and sodium chloride. In most instances, however, there were untoward reactions, most prominently a marked elevation of body temperature. Further study is obviously required to identify and remove the cause of the febrile reactions which in our experience have limited the clinical utility of this form of intravenous nutrition.
Databáze: OpenAIRE