Myonecrosis in three horses with colic: evidence for endotoxic injury

Autor:	C. V. Löhr, B. A. Valentine
Rok vydání:	2007
Předmět:	Pathology medicine.medical_specialty Necrosis General Veterinary biology business.industry Sand impaction High serum General Medicine medicine.disease Muscle injury Ulcerative colitis Colonic obstruction Stenosis biology.protein Medicine Creatine kinase medicine.symptom business
Zdroj:	Veterinary Record. 161:786-789
ISSN:	2042-7670 0042-4900
DOI:	10.1136/vr.161.23.786
Popis:	Three horses with colic, clinical evidence of endotoxaemia and high serum activities of creatine kinase and aspartate aminotransferase were examined postmortem. The horses were diagnosed with severe ulcerative colitis, pyloric ulceration and stenosis with colonic sand impaction, and colonic obstruction due to faecaliths. There was no gross or histological evidence of muscle trauma. Their semimembranosus muscles had scattered acute to subacute segmental necrosis of the myofibres, suggestive of endotoxin-induced muscle injury.
Databáze:	OpenAIRE
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