A Synthetic Approach to Anhydroketopyranoses Having a 6,8-Dioxabicyclo[3.2.1]octane Structure from Ketopyranoses

Autor:	Takashi Yamanoi, Kazuhide Matsumura, Yoshiki Oda, Sho Matsuda
Rok vydání:	2010
Předmět:	Pharmacology chemistry.chemical_compound Nucleophilic addition Glycosylation chemistry Reagent Organic Chemistry Intramolecular cyclization Ketose Combinatorial chemistry Analytical Chemistry Octane
Zdroj:	HETEROCYCLES. 82:531
ISSN:	0385-5414
DOI:	10.3987/com-10-s(e)24
Popis:	We investigated a synthetic approach to the anhydroketopyranoses having a 6,8-dioxabicyclo[3.2.1]octane structure from D -glucopyranose derivatives. The paper describes the nucleophilic addition of the organometallic reagents RLi or RMgX to the glucono-1,5-lactone derivatives to produce the ketopyranose derivatives having a glucose backbone and their intramolecular cyclization into the desired structural anhydroketopyranoses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3baf08041c769a5a946d99e8aa888840 https://doi.org/10.3987/com-10-s(e)24 Zobrazit plný text záznamu