Phomeketales A–F, six unique metabolites from the endophytic fungus Phoma sp. YN02-P-3
| Autor: | Bin Lin, Gang Chen, Hai-Feng Wang, Sheng-Ge Li, Xiao-Ni Li, Jiao Bai, Xia-Nan Sang, Xiao An, Yue-Hu Pei, Shao-Fei Chen |
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| Rok vydání: | 2016 |
| Předmět: |
biology
010405 organic chemistry Stereochemistry General Chemical Engineering chemistry.chemical_element General Chemistry Endophytic fungus biology.organism_classification 01 natural sciences 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry Phoma Spectral data Cytotoxicity Carbon Two-dimensional nuclear magnetic resonance spectroscopy |
| Zdroj: | RSC Advances. 6:64890-64894 |
| ISSN: | 2046-2069 |
| DOI: | 10.1039/c6ra12509c |
| Popis: | Phomeketales A–F (1–6), six new xyloketals, with unprecendented carbon substitution at C-16 and C-17 simultaneously, were isolated from the endophytic fungus Phoma sp. YN02-P-3. Their structures were elucidated on the basis of 1D and 2D NMR spectral data and ECD analysis. Compound 3 exhibited moderate anti-AChE activity and cytotoxicity against HL-60. |
| Databáze: | OpenAIRE |
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