Colangitis esclerosante secundaria en pacientes críticamente enfermos

Autor: Carlos Alberto Peña-Pérez, Juan Alberto Díaz Ponce-Medrano
Rok vydání: 2019
Předmět:
Zdroj: Cirugía y Cirujanos. 86
ISSN: 0009-7411
DOI: 10.24875/ciru.m18000003
Popis: Primary sclerosing cholangitis (PSC) is a rare idiopathic condition with immunopathogenic mechanisms where there is chronic progressive destruction of the biliary tree. Secondary sclerosing cholangitis (SSC) is clinically comparable to PSC, but is caused by specific processes which directly damage the biliary tree; examples include recurrent pancreatitis, bile duct malignancy, congenital bile duct abnormalities. A new cause of SSC has been described during or following significant critical illness associated with severe respiratory insufficiency, vasopressor requirement, shock and sepsis. This condition rapidly progresses to cirrhosis, frequently requiring liver transplantation for definitive management.
Databáze: OpenAIRE