Hypercortisolaemia and dyslipidaemia in a selected diabetic population
| Autor: | Taiwo Timilehin Darasimi, Afolabi Joy Oluwaseyifunmi, Ayodele Ademola Adelakun, Adediji Isaac Oluwole, Akinleye Waheed A |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
education.field_of_study Cholesterol business.industry Population medicine.disease Obesity chemistry.chemical_compound High-density lipoprotein Endocrinology Insulin resistance chemistry Internal medicine Post-hoc analysis medicine lipids (amino acids peptides and proteins) Analysis of variance education business Body mass index |
| Zdroj: | International Journal of Biomedical Research. 9:143 |
| ISSN: | 0976-9633 2455-0566 |
| DOI: | 10.7439/ijbr.v9i4.4538 |
| Popis: | Background: Type II DM and obesity are metabolic disorders characterized by insulin resistance, dyslipidaemia, and metabolic stress. These features were assessed in patients using fasting plasma glucose, fasting lipid profile and serum cortisol as their markers.Materials and methods: Ninety participants were recruited and classified into 3 groups of thirty each – Obese with type II DM, Non-obese with type II DM, non-obese and non-diabetics who served as controls. Anthropometric measures of weight and height were taken using standard procedures and body mass index was calculated thereafter. Blood samples were collected after an overnight fast for the in vitro assay of serum cortisol, plasma glucose, triglycerides, total cholesterol, low density lipoprotein cholesterol and high density lipoprotein cholesterol using enzyme linked immunosorbent assay and colorimetry as appropriate. Data obtained were analyzed statistically using ANOVA and post hoc test for comparison of variables between groups. Pearson’s correlation was performed to assess the relationship between variables and p |
| Databáze: | OpenAIRE |
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