Controlled release of drug molecules in metal–organic framework material HKUST-1
Autor: | Ning Lin, Qi-Wei Chen, Lian-Qiang Wei, Chong Zhuang, Qing Chen, Piao-Ping Tang |
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Rok vydání: | 2017 |
Předmět: |
Drug
media_common.quotation_subject 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Ibuprofen 01 natural sciences Controlled release 0104 chemical sciences Inorganic Chemistry chemistry.chemical_compound chemistry Chemical engineering Drug delivery Materials Chemistry medicine Molecule High surface area Organic chemistry Metal-organic framework Guaiacol Physical and Theoretical Chemistry 0210 nano-technology medicine.drug media_common |
Zdroj: | Inorganic Chemistry Communications. 79:78-81 |
ISSN: | 1387-7003 |
DOI: | 10.1016/j.inoche.2017.03.027 |
Popis: | The Cu3(BTC)2 metal–organic framework (MOF) (BTC = 1,3,5-benzenetricarboxylate), also known as HKUST-1, is one of the earliest reported stable MOFs with a very high surface area. In this study, HKUST-1 was used for the first time to absorb the pharmaceutical products of ibuprofen, anethole and guaiacol with loading amount of 0.34 g·g− 1, 0.38 g·g− 1 and 0.40 g·g− 1, respectively, which also showing good controlled drug release property. The result from this work provides a new attempt for HKUST-1 to be used as potential platform for drug delivery and release. |
Databáze: | OpenAIRE |
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