Controlled release of drug molecules in metal–organic framework material HKUST-1

Autor: Ning Lin, Qi-Wei Chen, Lian-Qiang Wei, Chong Zhuang, Qing Chen, Piao-Ping Tang
Rok vydání: 2017
Předmět:
Zdroj: Inorganic Chemistry Communications. 79:78-81
ISSN: 1387-7003
DOI: 10.1016/j.inoche.2017.03.027
Popis: The Cu3(BTC)2 metal–organic framework (MOF) (BTC = 1,3,5-benzenetricarboxylate), also known as HKUST-1, is one of the earliest reported stable MOFs with a very high surface area. In this study, HKUST-1 was used for the first time to absorb the pharmaceutical products of ibuprofen, anethole and guaiacol with loading amount of 0.34 g·g− 1, 0.38 g·g− 1 and 0.40 g·g− 1, respectively, which also showing good controlled drug release property. The result from this work provides a new attempt for HKUST-1 to be used as potential platform for drug delivery and release.
Databáze: OpenAIRE
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