Autor:	Stanley Burt, Gilda H. Loew
Rok vydání:	1980
Předmět:	Quantum chemical chemistry.chemical_compound chemistry Stereochemistry Antagonist Amine gas treating 4-Phenylpiperidine Quantum
Popis:	Summary Conformational analysis has been performed on a series of 3R, 4R-4ϕ-piperidine analogues which have antagonist activity that is modulated by substituents at these positions rather than at the amine nitrogen. Analysis of the results obtained by the semi-empirical quantum mechanical method PCILO has led to a consistent hypothesis to explain the structure-activity profiles of these new opiates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3b72c3a05c0fd937a8bb16b0bc5951be https://doi.org/10.1016/b978-0-08-025488-3.50012-x Zobrazit plný text záznamu