Effects of PTH and some synthetic fragments on embryonic bonein vitro
| Autor: | M. P. M. Herrmann-Erlee, J. W. Hekkelman, P. J. Gaillard |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Chemistry Endocrinology Diabetes and Metabolism Urinary system Parathyroid hormone chemistry.chemical_element Stimulation Peptide General Medicine Calcium Urinary calcium In vitro Endocrinology Biochemistry Internal medicine medicine Orthopedics and Sports Medicine Hormone |
| Zdroj: | Calcified Tissue Research. 21:70-74 |
| ISSN: | 1432-0827 0008-0594 |
| DOI: | 10.1007/bf02546430 |
| Popis: | Recent studies, employing the synthetic peptide bovine PTH 1–34 and analogues of this peptide have led to the conclusion that the amino terminal 1–34 or perhaps even the 1–27 residues of the hormone represent a structure sufficient for the expression of a series of biological effects: elevation of serum calcium; increase in urinary phosphate clearance and decrease of urinary calcium clearance; increase in urinary cyclic AMP; and the stimulation of adenyl cyclase activity in renal cortical membrane suspension in vitro (10, 14, 13, 16). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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