Opioid Control of Gonadotropin Secretion

Autor: B Preti, Mc Galassi, G. Comitini, S Bettelli, F Amato, Ar Genazzani, Stefano Angioni, N Tesorio, Felice Petraglia
Rok vydání: 1990
Předmět:
Zdroj: Endorphins in Reproduction and Stress ISBN: 9783540527367
Popis: Among the various neuropeptides which regulate gonadotropin secretion, endogenous opioid peptides (EOP) play an important role. Substantial evidence suggests a possible key function of for these peptides in the control of female reproduction. Infertility, for example, is typical in members of both sexes who abuse opiates. The major target of EOP in regulating reproductive function is control of the secretion of luteinizing hormone (LH), inhibiting the activity of hypothalamic neurons which produce gonadotropin-releasing hormone (GnRH). A possible action of opioids on pituitary and/or gonadal hormone secretion has also been demonstrated.
Databáze: OpenAIRE