Impact of B-Bloker therapy on right ventricular function in heart failure patients with reduced ejection fraction. A prospective evaluation
| Autor: | Alexis Gate-Martinet, J.B. Guichard, K. Isaaz, Cécile Romeyer, R. Galvès, A. Da Costa, Romain Pierrard |
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| Rok vydání: | 2020 |
| Předmět: |
education.field_of_study
medicine.medical_specialty Ejection fraction Ventricular function business.industry Population medicine.disease Prospective evaluation Therapy response Heart failure Internal medicine medicine Cardiology In patient Cardiology and Cardiovascular Medicine education Prospective cohort study business |
| Zdroj: | Archives of Cardiovascular Diseases Supplements. 12:38 |
| ISSN: | 1878-6480 |
| Popis: | Background s-Blocker Therapy has been shown to improve mortality and reduce hospitalizations in patients with heart failure (HF) with reduced ejection fraction (HFrEF). Its effects on right ventricular (RV) function have not been prospectively well studied. Objective. The aim of this prospective study was to: – evaluate if s-Blocker Therapy impacts RV remodelling based on echo parameters; – sought the echo predictive factors of s-Blocker therapy response. Methods From September 2017 to September 2018, HF patients were prospectively enrolled using CIBIS criteria: Class II, III, or IV HF; left ventricular ejection fraction (LVEF) Results Forty patients completing the study. The final population comprised 32 pts (79%): 2 did not tolerate s-Blocker therapy, 1 was lost of follow-up, 5 did not pursue the protocol. Several echo parameters significantly improved: LVEF from 31.7 ± 9 to 40.5 ± 9 (P Fig. 1 ). Conclusions In HFrEF patients, s-Blocker therapy significantly improves LV and RV systolic remodelling. |
| Databáze: | OpenAIRE |
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