611 Assessment of CYP3A Inhibition, Food Effect, and Glucose/insulin Changes with Prednisone Co-administration in a Phase 1 Trial of the Oral, ATP-competitive Akt Inhibitor GDC-0068

Autor:	A. Cervantes, Luna Musib, J. Tabernero, M.J. Dresser, Roel Funke, B.M. Liederer, N. Budha, Premal Patel, Raymond D. Meng, V. Malhi
Rok vydání:	2012
Předmět:	Cancer Research medicine.medical_specialty FOOD EFFECT CYP3A Chemistry Insulin medicine.medical_treatment Akt inhibitor Pharmacology Atp competitive Endocrinology Oncology Prednisone Internal medicine medicine Co administration medicine.drug
Zdroj:	European Journal of Cancer. 48:188
ISSN:	0959-8049
DOI:	10.1016/s0959-8049(12)72408-5
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3b3569c943dc3ed1fcd5102b955da718 https://doi.org/10.1016/s0959-8049(12)72408-5 Zobrazit plný text záznamu Full Text from ScienceDirect