Pancytopenia with Hemophagocytic Syndrome Associated with Histoplasmosis in Acquired Immunodeficiency Syndrome: Description of 2 Case Studies and Literature Review
| Autor: | Pradipta Guha, Dipanjan Bandyopadhyay, Sanjoy Kumar Chatterjee, Partha Sardar, Deeptarka Roy |
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| Rok vydání: | 2011 |
| Předmět: |
Pathology
medicine.medical_specialty biology business.industry Immunology Dermatology medicine.disease biology.organism_classification Pancytopenia Histoplasma capsulatum Histoplasmosis Histiocytosis Infectious Diseases medicine.anatomical_structure Acquired immunodeficiency syndrome (AIDS) hemic and lymphatic diseases Virology parasitic diseases medicine In patient Bone marrow Differential diagnosis business |
| Zdroj: | Journal of AIDS & Clinical Research. |
| ISSN: | 2155-6113 |
| DOI: | 10.4172/2155-6113.1000115 |
| Popis: | Two cases of haemophagocytic syndrome (HPS) due to histoplasmosis in patients with the acquired immunodeficiency syndrome (AIDS) are described in our case studies. Both the patients presented with pancytopenia and the bone marrow aspirate showed features suggestive of haemophagocytosis and the presence of intracellular inclusions were compatible with Histoplasma capsulatum. Haemophagocytic syndrome due to disseminated histoplasmosis should be included in the differential diagnosis of pancytopenia in patients with AIDS, though it is a rare clinical entity. |
| Databáze: | OpenAIRE |
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