Influence of the length of coronary artery lesions on fractional flow reserve across intermediate coronary obstruction

Autor: Mohammed Balgaith, Ali Alghamdi, Abdulaziz Al-Khaldi
Rok vydání: 2014
Předmět:
Zdroj: European Heart Journal Supplements. 16:B76-B79
ISSN: 1520-765X
DOI: 10.1093/eurheartj/suu010
Popis: The aim of the study was to assess the effect of coronary lesion length (LL) on fractional flow reserve (FFR) in coronary arteries with intermediate diameter stenosis (DS; 30– 60%). Eighty-three patients (89 lesions) with coronary artery disease underwent FFR measurement using a Radi or Volcano pressure wire. Diameter stenosis and LL were determined by quantitative coronary angiography, and the relationship between DS, LL, and FFR was assessed by regression analysis. Seventy-nine lesions had DS between 30 and 60% and were entered into the retrospective analysis. Mean DS and LL were 41.6 (+6.77%) and 9.2 (+6 mm), respectively. Fractional flow reserve ranged from 0.5 to 1.0. Pearson correlation coefficient for FFR vs. LL was 0.42 (P , 0.001). Using FFR ¼ 0.8 as a cut-off point, there was no difference in mean DS between the two subgroups (42 vs. 41.5%, P ¼ NS), while there was a significant difference in the LL (12.39 vs. 7.83 mm, P ¼ 0.002). In intermediate coronary artery lesion, there is a strong inverse correlation between FFR and LL.
Databáze: OpenAIRE