Einfluß von Glycylpressin auf den Ösophagusvarizendruck bei Patienten mit Leberzirrhose und vorangegangener Varizenblutung

Autor:	K H Meyer zum Büschenfelde, A. Rambow, M. Staritz
Rok vydání:	2008
Předmět:	medicine.medical_specialty Cirrhosis business.industry medicine.medical_treatment General Medicine medicine.disease Glycylpressin Gastroenterology Esophageal varices Internal medicine Sclerotherapy Medicine In patient business Varices
Zdroj:	DMW - Deutsche Medizinische Wochenschrift. 112:1292-1295
ISSN:	1439-4413 0012-0472
Popis:	In 15 patients with the history of bleeding from esophageal varices, confirmed cirrhosis of the liver (Child A) and esophageal varices (grade II, 2; grade III, 11; and grade IV, 2 patients) esophageal intravariceal pressures were endoscopically measured before and 10 min after intravenous administration of 1 mg glycylpressin. Pressures fell in the patients without previous sclerotherapy from 21.8 +/- 2.8 to 19.0 +/- 1.9 mm Hg (not significant), in those previously sclerosed from 18.0 +/- 1.4 to 14.5 +/- 1.0 mm Hg (p less than 0.05). In two of the non-sclerosed patients and one after sclerotherapy no change of pressure was recorded. The results indicate that glycylpressin has a relatively minor and uncertain effect on esophageal intravariceal pressure. In view of the possible side effects of the drug the indications for its use should be carefully weighed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3b1e197b3b2d96ffc0626d579e9af282 https://doi.org/10.1055/s-2008-1068238 Zobrazit plný text záznamu