Chemotherapeutische Behandlungsmöglichkeiten bei fortgeschrittenen Sarkomen

Autor:	Ch. Schmidt, M. Higi, W. Bierbaum, N. Firusian, Norbert Niederle, M. E. Scheulen, Seeber S, K. Bremer
Rok vydání:	2008
Předmět:	Oncology Cisplatin medicine.medical_specialty Vincristine Chemotherapy Ifosfamide business.industry medicine.medical_treatment Soft tissue General Medicine medicine.disease Radiation therapy Internal medicine medicine Doxorubicin Sarcoma business medicine.drug
Zdroj:	DMW - Deutsche Medizinische Wochenschrift. 106:1181-1185
ISSN:	1439-4413 0012-0472
DOI:	10.1055/s-2008-1070478
Popis:	43 patients with metastasizing sarcomas were treated with a combination of either vincristin, adriamycin and cis-platinum (n = 21) or ifosfamide and cis-platinum at three weeks' intervals in each case. Ten patients responded to the first combination and nine to the second combination with objective tumor regression. Particularly the latter result is remarkable since 16 of the 22 patients had already been pretreated with combinations containing adriamycin. Obviously the combination of ifosfamide and cis-platinum is a promising alternative in metastasizing sarcomas of the bones and soft tissue, especially if the CYVADIC combination--which is often regarded as standard treatment--remained unsuccessful. This has no bearing on additional surgical measures or on radiotherapy which may be necessary in some patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3b16e59e700af0d281e008d82051d759 https://doi.org/10.1055/s-2008-1070478 Zobrazit plný text záznamu