The consumption of antioxidant minerals copper, magnesium and selenium protects against cognitive and physical disabilities in elderly people with obesity
| Autor: | Fernando Isoard-Acosta, Miriam T López-Teros, Ana Bertha Pérez-Lizaur, César Hernández-Guerrero, Loredana Tavano-Colaizzi, Noemí Martínez-Castro |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Nutrition and Dietetics Antioxidant business.industry Thiobarbituric acid medicine.medical_treatment Medicine (miscellaneous) chemistry.chemical_element Physiology Lower risk medicine.disease_cause medicine.disease Obesity 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology chemistry medicine TBARS business Body mass index Selenium Oxidative stress |
| Zdroj: | Nutrición Hospitalaria. |
| ISSN: | 1699-5198 0212-1611 |
| Popis: | Introduction: antioxidants play an important role in the antioxidant defense system. Obesity and the aging process increase oxidative stress. The disruption of the oxidant-antioxidant balance towards oxidant condition could be related to cognitive and physical disabilities. Objective: to evaluate the consumption of antioxidants, the oxidative stress status and their relationship with cognitive and functional alterations in aged with obesity. Method: a cross-sectional study was conducted with 94 subjects ≥ 60 years stratified by body mass index (BMI) (76.6% were women). The antioxidants intake as well as cognitive and functional status were evaluated by validated surveys. The oxidative stress markers were thiobarbituric acid reactive substances (TBARS) and lipid-hydroperoxides (LOOH). Results: the antioxidants consumption of the participants was below the recommended daily intakes (RDI) independently of the BMI group. Especially, a lower consumption of vitamins E and D, selenium and β-carotenes was observed. The concentration of TBARS was higher (p < 0.05) in the obese (1.2 μM) versus the normal weight group (0.7 μM). The concentration of LOOH in the normal weight group (17 μM) did not show statistical difference versus obese group (15 μM). The presence of obesity in aged showed an association with walking difficulties. Multivariable analysis adjusted for several variables showed that the intake of selenium, copper and magnesium is associated with lower risk of cognitive and physical disabilities. Conclusions: aged with obesity showed a higher concentration of peripheral TBARS, walking difficulties and lower intake of antioxidants. The consumption of copper, selenium, and magnesium seems to protect against cognitive and physical disabilities in aged with obesity. |
| Databáze: | OpenAIRE |
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