Bacterial elimination via the photodynamic activity of a fullerene/light-harvesting antenna molecule assembled system integrated into liposome membranes
| Autor: | Daiki Antoku, Reo Ohdake, Kouta Sugikawa, Riku Kawasaki, Atsushi Ikeda |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Liposome
Fullerene derivatives Fullerene 010405 organic chemistry Chemistry High mortality General Engineering Bioengineering General Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Atomic and Molecular Physics and Optics 0104 chemical sciences Membrane Molecule General Materials Science Absorption (chemistry) Antenna (radio) |
| Zdroj: | Nanoscale Advances. 2:4395-4399 |
| ISSN: | 2516-0230 |
| Popis: | Ease of transmission and exceptionally high mortality rates make pathogen-based infections an ongoing global threat. Herein, a facile bacterial elimination process is described which is based on the photodynamic activity of fullerenes composed of light-harvesting antenna molecules integrated into liposome membranes. This was done to expand the absorption capabilities of fullerene derivatives. Efficient energy transfer from the photoactivated antenna molecules to the fullerenes enhanced antimicrobial activity without any harmful lytic activity against red blood cells even under irradiation. |
| Databáze: | OpenAIRE |
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