Beta-blockers and antithrombotic treatment for secondary prevention after acute myocardial infarction Towards an understanding of factors influencing clinical practice

Autor: N.B. Karatzas, A Reikvam, Antònia Agustí, C. Hagn, D. Ketley, Andrew M. Lowy, J Schilling, L Wilhelmsen, D. Vasiliauskas, R Kala, K.L. Woods, A Leizorowicz, R. Seabra-Gomes
Rok vydání: 1998
Předmět:
Zdroj: European Heart Journal. 19:74-79
ISSN: 0195-668X
DOI: 10.1053/euhj.1997.0560
Popis: Aims Long-term beta-blockade reduced mortality after acute myocardial infarction by about a quarter in a series of published trials. Representative data on beta-blocker use for secondary prevention are scanty but indicate wide variations. We have analysed European practice, and sources of variation, by regional sampling of acute myo-cardial infarction patients admitted to hospital in 11 countries during the period January 1993–June 1994. Methods and results Treatment data for 4035 representative patients were collected for the hospital phase and 6 months after discharge. A logistic regression model was developed to describe the predictors of beta-blocker use. In the 11 regional samples, 6–38% (20% overall) of patients had no recorded contraindications but were discharged without a beta-blocker. In the absence of perceived contraindications, there was a strong, independent negative association between age and odds of treatment ( P
Databáze: OpenAIRE