ЦИТОТОКСИЧЕСКОЕ ДЕЙСТВИЕ ПОЛИАКРИЛАТА ЗОЛОТА (АУРУМАКРИЛ) НА ФИБРОБЛАСТЫ КОЖИ ЧЕЛОВЕКА
Rok vydání: | 2020 |
---|---|
Předmět: | |
Zdroj: | Биофизика. 65:1093-1098 |
ISSN: | 0006-3029 |
DOI: | 10.31857/s0006302920060071 |
Popis: | The cytotoxic effect of the potential antitumor drug aurumacryl (aurum polyacrylate) on the hFB-hTERT6 human skin fibroblast cell line has been studied in vitro. It has been established that aurumacril exhibits substantial cytotoxicity to human skin fibroblasts. The maximum of cytotoxic effect (75% cell death) was observed when the concentration of aurumacryl was 0.125 mg/ml. The inhibitory concentration of aurumacryl causing 50% human skin fibroblast death (IC50) was 0.09 mg/ml. |
Databáze: | OpenAIRE |
Externí odkaz: |