ЦИТОТОКСИЧЕСКОЕ ДЕЙСТВИЕ ПОЛИАКРИЛАТА ЗОЛОТА (АУРУМАКРИЛ) НА ФИБРОБЛАСТЫ КОЖИ ЧЕЛОВЕКА

Rok vydání: 2020
Předmět:
Zdroj: Биофизика. 65:1093-1098
ISSN: 0006-3029
DOI: 10.31857/s0006302920060071
Popis: The cytotoxic effect of the potential antitumor drug aurumacryl (aurum polyacrylate) on the hFB-hTERT6 human skin fibroblast cell line has been studied in vitro. It has been established that aurumacril exhibits substantial cytotoxicity to human skin fibroblasts. The maximum of cytotoxic effect (75% cell death) was observed when the concentration of aurumacryl was 0.125 mg/ml. The inhibitory concentration of aurumacryl causing 50% human skin fibroblast death (IC50) was 0.09 mg/ml.
Databáze: OpenAIRE