Laboratory Diagnosis of Invasive Pneumococcal Disease
| Autor: | L. B. Reller, M. P. Weinstein, A. M. Werno, D. R. Murdoch |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Microbiology (medical)
medicine.medical_specialty Pneumococcal disease business.industry Diagnostic test Nucleic acid amplification technique bacterial infections and mycoses medicine.disease Vaccination Pneumococcal infections Pneumonia Infectious Diseases Immunology Pneumococcal pneumonia medicine Nucleic Acid Amplification Tests business Intensive care medicine |
| Zdroj: | Clinical Infectious Diseases. 46:926-932 |
| ISSN: | 1537-6591 1058-4838 |
| DOI: | 10.1086/528798 |
| Popis: | The laboratory diagnosis of invasive pneumococcal disease (IPD) continues to rely on culture-based methods that have been used for many decades. The most significant recent developments have occurred with antigen detection assays, whereas the role of nucleic acid amplification tests has yet to be fully clarified. Despite developments in laboratory diagnostics, a microbiological diagnosis is still not made in most cases of IPD, particularly for pneumococcal pneumonia. The limitations of existing diagnostic tests impact the ability to obtain accurate IPD burden data and to assess the effectiveness of control measures, such as vaccination, in addition to the ability to diagnose IPD in individual patients. There is an urgent need for improved diagnostic tests for pneumococcal disease--especially tests that are suitable for use in underresourced countries. |
| Databáze: | OpenAIRE |
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