Potential uses and Analysis of Bioactive Natural Compounds of Peganum harmala

Autor: Israa Adnan Ibraheam, Imad Hadi Hameed, Haider Mashkoor Hussein
Rok vydání: 2018
Předmět:
Zdroj: International Journal of Pharmaceutical Quality Assurance. 9
ISSN: 0975-9506
DOI: 10.25258/ijpqa.v9i2.13638
Popis: Peganum harmala is of Asian Origin and grows in the Middle East and in part of South Asia mainly in India and Pakistan. In Iran, and some countries in the Arab world such as, Syria, Iraq, Saudi Arabia and Jordan, dried capsules mixed with other ingredients are placed onto red hot charcoal, where they explode with little popping noises in a way similar to American popcorn. Peganum harmala has been used to treat pain and to treat skin inflammations, including skin cancers. Some of these alkaloids such as harmaline, harmine, and norharmane are also endogenous compounds present in the body and since they have been found in high plasma concentrations in alcoholics, drug addicts, smokers, and patients with Parkinson's disease, they are thought to be crucially involved in various central nervous system (CNS) problems. All of these effects represent an idea that P. harmala and its derivatives could be used for treatment of mood disorders and are potent alternatives for current anti-depression drugs.
Databáze: OpenAIRE