Simultaneous Evaluation of Magnesia and Silica Contents’ Effect onin-vitroBioactivity of Novel Bioglasses in the SiO2-CaO-MgO System
| Autor: | Vahid Maddahi, Masoud Eslami, Zahra Mahdieh, Mohammad Ali Shokrgozar, Morteza Mehrjoo |
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| Rok vydání: | 2016 |
| Předmět: |
010302 applied physics
Materials science Magnesium chemistry.chemical_element Mineralogy Osteoblast 02 engineering and technology 021001 nanoscience & nanotechnology 01 natural sciences In vitro Apatite Amorphous solid medicine.anatomical_structure Compressive strength chemistry visual_art 0103 physical sciences Ceramics and Composites medicine visual_art.visual_art_medium MTT assay Particle size 0210 nano-technology Nuclear chemistry |
| Zdroj: | Transactions of the Indian Ceramic Society. 75:7-11 |
| ISSN: | 2165-5456 0371-750X |
| DOI: | 10.1080/0371750x.2015.1131628 |
| Popis: | In this study, bioglasses in SiO2-CaO-MgO system were synthesized through sol-gel method and the effect of silica and magnesia contents on in-vitro bioactivity of the bioglasses were investigated. XRD patterns showed an amorphous structure after heat treatment at 600°C for 2 h for all glasses and also indicated that after immersion in SBF, apatite particles precipitated on glass surfaces and the rate of apatite formation decreased with increasing Mg/Ca ratio. On the other hand, the apatite formation rate was enhanced with increasing the silica content. Furthermore, magnesia contents increased the compressive strength of the samples. According to SEM, higher Mg/Ca ratio led to increase in particle size of the precipitated apatite. MTT assay showed that cell proliferation was inhibited with increasing Mg/Ca ratio, however, silica contents stimulated the osteoblast proliferation. |
| Databáze: | OpenAIRE |
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