The Use of Flow Chemistry for Two-Phase Dibromocyclopropanation of Alkenes

Autor:	Yngve Stenstrøm, Runa Berg Østby, Terje Didriksen
Rok vydání:	2015
Předmět:	Fluid Flow and Transfer Processes Green chemistry chemistry.chemical_classification Base (chemistry) Organic Chemistry Inorganic chemistry Nanochemistry Flow chemistry chemistry.chemical_compound chemistry Chemistry (miscellaneous) Phase (matter) Bromoform Microreactor
Zdroj:	Journal of Flow Chemistry. 5:69-73
ISSN:	2063-0212 2062-249X
Popis:	Conventional batch dibromocyclopropanations by reaction of bromoform and alkenes under phase-transfer conditions require strong base (50% NaOH (aq)), vigorous stirring, and often long reaction times. Using flow chemistry in a microreactor, the reactions were found to be smooth, rapid, and high-yielding under ambient conditions when 40% (w/w) NaOH was used as the base. The reaction has been tested with a representative selection of alkenes, displaying a variety of structural features.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3a78b46572a5f8998fd88345b18c94b3 https://doi.org/10.1556/jfc-d-14-00041 Zobrazit plný text záznamu Full text from SpringerLink