Nucleic acid binding properties of thyminyl and adeninyl pyrrolidine-amide oligonucleotide mimics (POM)This paper is dedicated to Professor Heinz G. Floss on the occasion of his 70th birthday.Electronic supplementary information (ESI) available: experimental details. See http://www.rsc.org/suppdata/cc/b3/b315768g
| Autor: | David T. Hickman, Jordi Morral, Ian Beadham, T. H. Samuel Tan, Jason Micklefield |
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| Rok vydání: | 2004 |
| Předmět: |
animal structures
Oligonucleotide Metals and Alloys RNA General Chemistry Combinatorial chemistry Catalysis Pyrrolidine Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry.chemical_compound Nucleic Acid Denaturation chemistry Amide Complementary DNA Materials Chemistry Ceramics and Composites Nucleic acid sense organs DNA |
| Zdroj: | Chemical Communications. :516 |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/b315768g |
| Popis: | Adeninyl POM was prepared using solid-phase peptide chemistry and shown to exhibit higher affinity for complementary DNA and RNA than the corresponding adeninyl PNA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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