Degradation of Rabeprazole-N-oxide in aqueous solution using sonication as an advanced oxidation process

Autor: Nalini Vijayalaximi Pedamalla, P. Saritha, D. Bhagawan, G. Shankaraiah, V. Himabindu
Rok vydání: 2014
Předmět:
Zdroj: Journal of Environmental Chemical Engineering. 2:510-515
ISSN: 2213-3437
DOI: 10.1016/j.jece.2013.10.007
Popis: The degradation of Rabeprazole-N-oxide with sonication (US), peroxide mediated sonication (US/H 2 O 2 ), Sono-Fenton (US/Fenton), TiO 2 mediated sonication (US/TiO 2 ) and sonication in combination with H 2 O 2 and TiO 2 (US/TiO 2 + H 2 O 2 ) is investigated and compared for their treatment efficiency. The effects of the frequency, power, different reactant concentrations and pH on the degradation rate have been examined. The efficiency of the treatment system is measured in terms of compound degradation and COD reduction. Among all the treatment processes studied, US/TiO 2 + H 2 O 2 is observed to be effective in degrading the drug impurity. A maximum of 72% degradation of the compound is observed at pH 7 with 50 mg of TiO 2 and peroxide concentration of 500 mg/L.
Databáze: OpenAIRE