Perinatal outcome after selective feticide in monochorionic twin pregnancies

Autor: Frans J.C.M. Klumper, J. M. M. van Klink, E. M. van den Bos, Enrico Lopriore, Dick Oepkes, Johanna M. Middeldorp
Rok vydání: 2013
Předmět:
Zdroj: Ultrasound in Obstetrics & Gynecology. 41:653-658
ISSN: 0960-7692
DOI: 10.1002/uog.12408
Popis: Objective To evaluate the incidence and risk factors of adverse perinatal outcome in complicated monochorionic twin pregnancies treated with selective feticide. Methods This was a retrospective analysis of prospectively collected data from a consecutive, national cohort. All monochorionic twin pregnancies treated with selective feticide at Leiden University Medical Center between June 2000 and November 2011 were included. Obstetric and neonatal data were recorded. The primary outcome measure was adverse perinatal outcome, including fetal or neonatal demise or severe neonatal morbidity. Results Data on perinatal outcome were obtained in all cases (n =131). Overall perinatal survival rate was 67.2% (88/131). Median gestational age at delivery was 34 (interquartile range, 23–38) weeks. Neonatal mortality and morbidity rate in liveborn children was 4.3% (4/92) and 12.0 % (11/92), respectively. Severe cerebral injury was detected in three children. The overall incidence of adverse perinatal outcome was 41.2% (54/131). Median gestational age at occurrence of preterm prelabor rupture of membranes (PPROM) was 19.0weeks and 32.0weeks in cases with and without adverse perinatal outcome, respectively (P =0.017). Liveborn children with adverse perinatal outcome were born at a lower median gestational age (29.0weeks) than were children without adverse perinatal outcome (38.0weeks) (P
Databáze: OpenAIRE
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