Notice of Removal: Sensitization of hypoxic tumors to radiation therapy using ultrasound sensitive oxygen microbubbles

Autor: Maria Stanczak, Ji-Bin Liu, Patrick O'Kane, Margaret A. Wheatley, Jingzhi Li, John R. Eisenbrey, Rawan Shraim, Brian E. Oeffinger, Flemming Forsberg
Rok vydání: 2017
Předmět:
Zdroj: 2017 IEEE International Ultrasonics Symposium (IUS).
DOI: 10.1109/ultsym.2017.8092222
Popis: Tumor hypoxia has been shown to decrease the sensitivity of solid tumors to radiation. Systemic efforts to increase tumor oxygenation levels immediately prior to therapy, however, have largely proven unsuccessful. The objective of this work was to determine the utility of oxygen-filled, ultrasound sensitive microbubbles for locally delivering oxygen and sensitizing tissue to radiation in a breast cancer model.
Databáze: OpenAIRE