| Autor: |
Alexei D. Kolotii, Kurinnaia Os, Svetlana G. Vorsanova, Yuri B. Yurov, Ivan Y. Iourov |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Human Interphase Chromosomes ISBN: 9783030625313 |
| DOI: |
10.1007/978-3-030-62532-0_7 |
| Popis: |
Interphase molecular cytogenetics provides opportunities for analysis of chromosomes in almost all types of human cells at any stage of the cell cycle. Generally, interphase fluorescence in situ hybridization (I-FISH) is a basic technological platform for visualization of individual chromosomes (chromosomal regions) in single cells. The achievements of studying human interphase chromosomes have allowed numerous discoveries in chromosome research (molecular cytogenetics) and genomics (cytogenomics). In the postgenomic era, interphase chromosome analysis by I-FISH remains an important part of biomedical research. Here, we describe the spectrum of FISH applications with special emphasis on interphase chromosome biology and molecular cytogenetic/cytogenomic diagnosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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