Application of a pet device with 1.5 mm FWHM intrinsic spatial resolution to breast cancer imaging

Autor: D. Narayanan, Nadine M. Lesko, D. Beylin, J. Hummel, Mohan Doss, William Peter, Judy V. Lovelace, Rita I. Freimanis, K. Lauckner, S.D. Wollenweber, P. Stepanov, Michael H. Torosian, Irving N. Weinberg, V. Zavarzin, Rodney C. Williams, Kathryn A. Morton, Lee P. Adler, Edward A. Levine, S. Yarnall, Elin R. Sigurdson, Kim R. Geisinger, E.V. Anashkin, K. Evers, Nancy D. Perrier, S. Dolinsky
Rok vydání: 2005
Předmět:
Zdroj: ISBI
Popis: Operation of a high resolution compact clinical PET Scanner (PEM Flex/spl trade/) device as a breast scanner is described. The device features high spatial resolution (1.5 mm FWHM intrinsic resolution) as a result of small crystals and compact position-sensitive photomultipliers. The compactness of the system allows it to reside within a stereotactic X-ray mammography unit, or as a separate standalone system capable of breast compression. The gamma rays are detected for a volumetric reconstruction by two heads, each of which contains 2,028 2 mm by 2 mm by 10 mm lutetium-containing crystals. The heads travel within X-ray transparent compression paddles. A window is provided in one of the paddles for direct correlation with ultrasound transducers and for interventional access. To enable real-time interventions, images are reconstructed and displayed while the detectors are still acquiring data. The maximum-likelihood reconstruction provides quantitative images with threefold improved contrast as compared to simple back-projections.
Databáze: OpenAIRE