COGNITIVE BEHAVIOR THERAPY FOR COMORBID OBSESSIVE-COMPULSIVE DISORDER IN HIGH-FUNCTIONING AUTISM SPECTRUM DISORDERS: A RANDOMIZED CONTROLLED TRIAL
| Autor: | Isobel Heyman, Declan G. Murphy, Kate Johnston, Miguel A. Fullana, David Mataix-Cols, Hilary Mack, Amita Jassi, Ailsa Russell |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment medicine.disease behavioral disciplines and activities law.invention High-functioning autism Psychiatry and Mental health Clinical Psychology Randomized controlled trial law Asperger syndrome Autism spectrum disorder mental disorders medicine Cognitive therapy Autism Anxiety medicine.symptom Psychology Psychiatry Anxiety disorder Clinical psychology |
| Zdroj: | Depression and Anxiety. 30:697-708 |
| ISSN: | 1091-4269 |
| Popis: | Background: High rates of anxiety disorders, particularly obsessive compulsive disorder (OCD) are reported in people with Autism spectrum disorders (ASD). Group cognitive behavioral treatment (CBT) has been found effective for anxiety in young peoplewith ASD but notbeen OCD specific.One uncontrolledpilotstudy of individual CBT for OCD for adults with ASD showed good treatment efficacy. Methods: Forty-six adolescents and adults (mean age 26.9 years, 35 Males) with ASD and comorbid OCD were randomized to CBT for OCD or anxiety management (AM), a plausible control treatment. Treatments were matched in duration (mean of 17.4 sessions CBT; 14.4 sessions AM), the Yale–Brown Obsessive Compulsive Severity Scale (YBOCS) as primary outcome measure and evaluations blind to treatment group. Treatment response was defined as > 25% reduction in YBOCS total severity scores. Results: Both treatments produced a significant reduction in OCD symptoms, within-group effect sizes of 1.01 CBT groupand0.6fortheAMgroup.Therewerenostatisticallysignificantdifferences between the two groups at end of treatment, although more responders in the CBT group (45 versus 20%). Effect sizes for self-rated improvement were small (0.33 CBT group; –0.05 AM group). Mild symptom severity was associated with improvement in the AM but not the CBT group. Family/carer factors were importantforbothgroups,inthatincreasedfamilyaccommodationwasassociated with poorer outcome. Conclusions: Evidence-based psychological interventions, both AM and CBT, were effective in treating comorbid OCD in young people and adults with ASD. Depression and Anxiety 30:697–708, 2013. C |
| Databáze: | OpenAIRE |
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