124 Maternal Blood S100B Levels in Pregnancies Complicated by Fetal Growth Restriction May Early Predict the Occurrence of Intraventricular Hemorrhage
| Autor: | Daniela Dores, Raffaele Battista, C. G. Guidoni, Chiara Voltolini, Fabrizio Michetti, Diego Gazzolo, Enrico Picciolini, Michela Torricelli, E Scarpetti, Felice Petraglia, Pasquale Florio |
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| Rok vydání: | 2005 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Obstetrics Ultrasound Gestational age Neurological examination Maternal blood Laser Doppler velocimetry medicine.disease Intraventricular hemorrhage medicine.artery Pediatrics Perinatology and Child Health Middle cerebral artery medicine Fetal growth business reproductive and urinary physiology |
| Zdroj: | Pediatric Research. 58:376-376 |
| ISSN: | 1530-0447 0031-3998 |
| DOI: | 10.1203/00006450-200508000-00153 |
| Popis: | The aim of these present study was to evaluate maternal levels of S100B (a neural protein found in high concentrations in biological fluids after cell injury in the nervous system), in pregnancies complicated by intrauterine growth retardation (IUGR) and to correlate after their measurements with postnatal intraventricular hemorrhage (IVH) occurrence. A case-control study in pregnant women complicated by IUGR(n= 106) of whom a subgroup (n=26) developed postnatal IVH, and a group of normal pregnancies (n=212) matched for gestational age served as control. Ultrasound scanning, Doppler velocimetry patterns (in the utero-placental and in the middle cerebral artery vessels), and maternal blood samples were collected before birth in all women with IUGR. After birth routine laboratory parameters, cerebral ultrasound patterns and neurological examination were recorded in IUGR and control newborns. |
| Databáze: | OpenAIRE |
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