Quantitative analysis on optical properties of human atherosclerosis by using polarization-sensitive optical coherence tomography

Autor: Ming Wei Hsiung, Po Nien Yang, Nai-Kuan Chou, Jeou-Jong Shyu, Wen Chuan Kuo
Rok vydání: 2008
Předmět:
Zdroj: SPIE Proceedings.
ISSN: 0277-786X
DOI: 10.1117/12.762170
Popis: In this research, we have used an algorithm to extract four different optical parameters, including the scattering coefficient (μ s ), effective anisotropy factor (g off ), birefringence coefficient (Δn), and fast-axis angle (β) from polarization-sensitive optical coherence tomography (PS-OCT) images. The proposed method was evaluated from a set of phantoms and it yielded valid results. We demonstrate that the optical characteristic of normal and different kinds of atherosclerotic lesions in human vessel can be quantitatively described. Whether change in these quantified optical properties could be used to discriminate between different types of human atherosclerotic plaques was examined.
Databáze: OpenAIRE