Toxicologic evaluation of individual chemical compounds and their complex mixtures using a motile cell test object
| Autor: | Kaiumov Ri, Lappo Vg, Rotenberg IuS, Aref'ev Im, Es'kov Ap |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
chemistry.chemical_classification
endocrine system Chromatography urogenital system Cell Motility General Medicine Polymer Biology Test object General Biochemistry Genetics and Molecular Biology Acute toxicity Cell biology medicine.anatomical_structure chemistry Toxicity medicine Spermatozoa motility reproductive and urinary physiology |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 105:59-62 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00835458 |
| Popis: | The possibility of quantitative prognosis of chemical compounds and complex mixtures toxicity by means of a biotechnical system with suspension of bull spermatozoa sensor was investigated. The concentration of some chemical compounds, inhibiting by half spermatozoa motility has been experimentally determined. A correlation between the values determined and acute toxicity of the compounds tested has been established. The possible use of the biotechnical system for the screening of medical polymer materials has been demonstrated. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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