Synthesis and reactions of 3-thioxo[1,2,4]-triazino[3,2-b]quinazolin-10-ones

Autor:	Yehia A. Ibrahim, Ali M. El-Zanaty, Mohga M. Eid
Rok vydání:	1990
Předmět:	chemistry.chemical_compound Aniline Chemistry Organic Chemistry Chemical conversion Hydrazine Organic chemistry Ring (chemistry) Medicinal chemistry
Zdroj:	Journal of Heterocyclic Chemistry. 27:591-593
ISSN:	1943-5193 0022-152X
DOI:	10.1002/jhet.5570270322
Popis:	Thiation of [1,2,4]triazino[3,2-b]quinazoline-3,10-dione 1 proceeds selectively to give the 3-thioxo-analog 3. The latter was converted to the corresponding 3-methylthio derivative 4 which was reacted with aniline and hydrazine to give the corresponding anilino- and hydrazino derivatives 5 and 7. Compound 7 was converted to the hydrazones 8a,b and into the novel heterocyclic ring systems [1,2,4]triazolo[4′,3′:4,5][1,2,4]triazino-[3,2-b]quinazolin-7-ones 9, 10a,b and tetrazolo[1′,5′:4,5][1,2,4]triazino[3,2-b]quinazolin-7-one 11.
Databáze:	OpenAIRE
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