Efficacious Preparation of Oppolzer’s Glycylsultam via the Delépine Reaction

Autor:	Philip Garner, Carolyn Gonsky, Robert C. Ronald, Alper Isleyen
Rok vydání:	2009
Předmět:	chemistry.chemical_compound Chemistry Component (thermodynamics) Reagent Organic Chemistry Enantioselective synthesis Molecule Organic chemistry Combinatorial chemistry Delépine reaction Catalysis Pyrrolidine Coupling reaction
Zdroj:	Synthesis. 2009:1261-1264
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0028-1088021
Popis:	A new preparative route to Oppolzer's glycylsultam, the 'NC' component in the asymmetric [C+NC+CC] coupling reaction leading to functionalized pyrrolidines, is described. The synthesis features a novel application of the Delepine reaction, providing a safe, efficient, and environmentally benign route to this useful chiral reagent for pyrrolidine synthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::39f49b480f97e0516428bce0f4e78233 https://doi.org/10.1055/s-0028-1088021 Zobrazit plný text záznamu