Immunologic alterations in xeroderma pigmentosum patients

Autor: Marcello H. Grunwald, Albert I. Pick, Arjeh J. Wysenbeek, Malka Duczyminer-Kahana, Haya Weiss
Rok vydání: 1986
Předmět:
Zdroj: Cancer. 58:219-221
ISSN: 1097-0142
0008-543X
Popis: Nine xeroderma pigmentosum (XP) patients were investigated. In comparison to a normal control group the XP patients had a reduced OKT-4 lymphocyte subpopulation, reduced response of lymphocytes to phytohemagglutinin in autologous serum, and diminished delayed hypersensitivity skin reaction. The possible contribution of ultraviolet irradiation to the observed immunologic alterations, and the link of these alterations to the susceptibility of patients for malignant transformation is discussed. Cancer 58:219–221, 1986.
Databáze: OpenAIRE