Effect of adrenal cortical hormones on I131 absorption by the thyroid and on the respiration of its parenchyma
| Autor: | V. V. Natarov |
|---|---|
| Rok vydání: | 1964 |
| Předmět: |
medicine.medical_specialty
Chemistry Thyroid General Medicine urologic and male genital diseases Thyroid Gland Tissue General Biochemistry Genetics and Molecular Biology Excretion medicine.anatomical_structure Endocrinology Internal medicine Parenchyma Respiration medicine Cortisone Desoxycorticosterone Acetate hormones hormone substitutes and hormone antagonists Hormone medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 57:187-190 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00783538 |
| Popis: | The influence of cortisone-acetate and desoxycorticosterone acetate (DOCA) on absorption and excretion of I131 by the thyroid gland depends on the dose and the length of action of the hormonal preparations. The action of DOCA (1.5 mg per 100 gm of body weight) and of cortisone (1.5 mg per 100 gm of body weight) varies; this is manifested in different periods of appearance of the maximal iron radioactivity (in experiments with DOCA−3 days, with cortisone−5), its value (in DOCA more, than in cortisone), and in the nature of action (on the 3rd day DOCA increases, and cortisone reduces the isotope absorption as compared to control). In experiments in vitro carried out in a Warburg apparatus cortisone-acetate and DOCA changed the respiration of the thyroid gland tissue. A rise in the cortisone dose (0.4-1.0-4.7 mg) caused a parallel rise in the oxygen intake by the thyroid gland, whereas DOCA intensified the respiration of the thyroid parenchyma only in a medium dose (1.5 mg). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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