INTERACTION OF A MODEL OPIATE ANIONIC RECEPTOR SITE WITH N-SUBSTITUENTS OF RIGID OPIATES: PCILO ENERGY CALCULATIONS

Autor:	Gilda H. Loew, Stanley Burt
Rok vydání:	1980
Předmět:	Agonist Quantum chemical method medicine.drug_class Chemistry Stereochemistry medicine Antagonist Opiate Ring (chemistry) Receptor
DOI:	10.1016/b978-0-08-025488-3.50015-5
Popis:	The interaction of a model anionic receptor site with a series of N-substituents of fused ring opiates have been characterized using the semi-empirical quantum chemical method, PCILO. The results are examined for their implications for induced opiate- receptor binding and agonist/antagonist activity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::39c04f76fe2fd7b7d9b7c2e9db88883a https://doi.org/10.1016/b978-0-08-025488-3.50015-5 Zobrazit plný text záznamu