The Antigenic Structure of Treponema Pallidum, Nichols Strain

Autor:	James N. Miller, J. H. De Bruijn, J. H. Bekker, P. C. Onvlee
Rok vydání:	1966
Předmět:	Immunology Immunology and Allergy
Zdroj:	The Journal of Immunology. 96:450-458
ISSN:	1550-6606 0022-1767
DOI:	10.4049/jimmunol.96.3.450
Popis:	Summary Relatively tissue-free suspensions of Treponema pallidum, Nichols strain, were prepared by extracting the organism in rabbit serum-saline medium in equal parts. They were exposed to ultrasonic disintegration and the presence of antigens within the lysate and residue determined. Heat-labile and heat-stable (non-cardiolipin) antigens specific for T. pallidum, as well as antigens related to the lipopolysaccharide and protein (RP) components of the nonpathogenic Treponema reiteri, could be demonstrated. Further, the above antigens were shown to be unrelated to TPI antigen(s). The specific T. pallidum antigens within the lysate were found to be distinct from those within the residue.
Databáze:	OpenAIRE
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