Highly Diastereoselective Michael Addition Reactions of Lithium Enolates to Ethyl 3-Trifluoromethylacrylate

Autor: Jiro Haga, Tomoya Kitazume, Takashi Yamazaki, Shinichiro Nakamura
Rok vydání: 1991
Předmět:
Zdroj: Chemistry Letters. 20:2171-2174
ISSN: 1348-0715
0366-7022
DOI: 10.1246/cl.1991.2171
Popis: Michael addition reactions of lithium enolates derived from ketones, esters, and amides to ethyl 3-trifluoromethylacrylate were found to proceed smoothly in moderate to excellent chemical yields as well as with a high degree of diastereoselectivity at the newly formed carbon–carbon bond.
Databáze: OpenAIRE