The role of allogenic keratin-derived dressing in wound healing in a mouse model

Autor: Aandrzej W. Lipkowski, Dorota Sulejczak, Aleksandra Misicka, Joanna Czuwara, Marek Konop, Piotr Kosson, Lidia Rudnicka
Rok vydání: 2017
Předmět:
Zdroj: Wound Repair and Regeneration. 25:62-74
ISSN: 1067-1927
DOI: 10.1111/wrr.12500
Popis: Keratin is an interesting protein needed for wound healing and tissue recovery. We have recently proposed a new, simple and inexpensive method to obtain fur and hair keratin-derived biomaterials suitable for medical application. The aim of the study was to evaluate the role of the fur keratin derived protein (FKDP) dressing in the allogenic full-thickness surgical skin wound model. Results: The data obtained using scanning electron microscopy showed that employed processed biomaterial had higher surface porosity compared to control raw material. From the MTS test, it was found keratin biomaterial is not only toxic to the NIH/3T3 cell line (p
Databáze: OpenAIRE
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