The role of allogenic keratin-derived dressing in wound healing in a mouse model
Autor: | Aandrzej W. Lipkowski, Dorota Sulejczak, Aleksandra Misicka, Joanna Czuwara, Marek Konop, Piotr Kosson, Lidia Rudnicka |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
chemistry.chemical_classification Pathology medicine.medical_specialty integumentary system Skin wound Cell growth Chemistry Biomaterial 02 engineering and technology Dermatology 021001 nanoscience & nanotechnology 03 medical and health sciences 030104 developmental biology In vivo Cell culture Keratin medicine Surgery Wound closure 0210 nano-technology Wound healing |
Zdroj: | Wound Repair and Regeneration. 25:62-74 |
ISSN: | 1067-1927 |
DOI: | 10.1111/wrr.12500 |
Popis: | Keratin is an interesting protein needed for wound healing and tissue recovery. We have recently proposed a new, simple and inexpensive method to obtain fur and hair keratin-derived biomaterials suitable for medical application. The aim of the study was to evaluate the role of the fur keratin derived protein (FKDP) dressing in the allogenic full-thickness surgical skin wound model. Results: The data obtained using scanning electron microscopy showed that employed processed biomaterial had higher surface porosity compared to control raw material. From the MTS test, it was found keratin biomaterial is not only toxic to the NIH/3T3 cell line (p |
Databáze: | OpenAIRE |
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