Comparative assessment of diagnostic value of computed tomography and contrast-enhanced ultrasound in colorectal cancer liver metastases diagnosis

Autor: Ekaterina A. Busko, Kseniya V. Kozubova, Sergey S. Bagnenko, Aleksey M. Karachun, Ilya A. Burovick, Anastasiya B. Goncharova, Ekaterina V. Kostromina, Roman A. Kadyrleev, Indira H. Kurganskaya, Lev N. Shevkunov
Rok vydání: 2022
Předmět:
Zdroj: Annaly khirurgicheskoy gepatologii = Annals of HPB Surgery. 27:22-32
ISSN: 2408-9524
1995-5464
Popis: Aim: This study aimed to clarify the ultrasound semiotics of colorectal cancer liver metastases contrast enhancement, and perform a comparative assessment of the diagnostic efficacy of contrast-enhanced ultrasound and computed tomography (CT).Methods: We studied 40 patients with colorectal cancer: patients receiving treatment for the disease and having newly diagnosed colorectal cancer. All patients underwent contrast-enhanced ultrasound and CT. In the cases of suspected malignancy, a trephine biopsy and a morphological examination were performed.Results: Contrast-enhanced ultrasound and CT demonstrated comparable and high diagnostic efficacy. The sensitivity of the contrast-enhanced ultrasound in malignancy detection was 93.3%, with 90% specificity, 96.55% positive predictive value, 81.82% negative predictive value, and 92.5% accuracy. The sensitivity of contrast-enhanced CT was 93.3%, with 80% specificity, 93.33% positive predictive value, 80% negative predictive value, and 92.5% accuracy.Conclusions: For patients with colorectal cancer with contraindications to contrast-enhanced CT, contrast-enhanced ultrasound may be used an alternative imaging option for the differential diagnosis of liver neoplasms.
Databáze: OpenAIRE