Measurement of liver blood flow parameters combined with near-infrared spectroscopy
| Autor: | 张晓枫 Zhang Xiao-feng, 辛桂杰 Xin Gui-jie, 焦阳 Jiao Yang, 刘光达 Liu Guang-da, 徐国忠 Xu Guo-zhong |
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| Rok vydání: | 2012 |
| Předmět: |
Observational error
Materials science Absorption spectroscopy Pulse (signal processing) business.industry Near-infrared spectroscopy Hemodynamics Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials chemistry.chemical_compound Optics chemistry Pulse wave Arterial blood business Indocyanine green Biomedical engineering |
| Zdroj: | Optics and Precision Engineering. 20:2140-2146 |
| ISSN: | 1004-924X |
| DOI: | 10.3788/ope.20122010.2140 |
| Popis: | A pulse spectroscopic scheme based on dye dilution and an excretion test was developed to overcome the shortcomings of conventional blood dye concentration measuring method in complex operation,invasive treatment and non-continuance.Firstly,Indocyanine Green(ICG) was intravenously injected and a finger clip sensor was used to extract spectral signals of fingertips for a sufferer.Then,by recording the dye dilution curve simultaneously,the algorithm to isolate ICG absorption spectrum from the disturbance of peripheral arterial blood was implemented.Finally,the ICG plasma disappearance rate K,15 min retention rate R15and other hepatic hemodynamic parameters were deduced by analyzing the semi-logarithmic dye concentration graph.Combining a lab-VIEW software platform with an adaptive differential threshold method,proposed scheme eliminates the interference come from the hemoglobin absorption spectrum and baseline drift,improves the measuring accuracy greatly,and the average measurement error of K is less than 0.008.This method is great value to not only the assessing hepatic functional reserve at pre-operation,intra-operation,post-operation,but also providing a way to monitor some middle variables for clinical research purposes. |
| Databáze: | OpenAIRE |
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