Identification of genetic marker for prolactin gene related to milk yield in pedigreed Sahiwal population

Autor:	Ekta Rana, Arumugam Kumaresan, B.S. Pradeep Nag, A.K. Chakravarthy, Aneet Kour, Saleem Yousuf, T. Karuthadurai, D. Ravikumar
Rok vydání:	2018
Předmět:	0301 basic medicine Veterinary medicine education.field_of_study General Veterinary Population Biology 03 medical and health sciences Exon Restriction enzyme 030104 developmental biology Milk yield Genetic marker Genotype SNP Animal Science and Zoology Allele education
Zdroj:	Indian Journal of Animal Research.
ISSN:	0976-0555 0367-6722
DOI:	10.18805/ijar.b-3578
Popis:	The study was conducted to identify the genetic marker for prolactin gene related to milk yield in pedigreed Sahiwal population. PCR-RFLP was carried out by using Rsa1 restriction endonuclease and revealed three genotypes GG, GA and AA in Sahiwal population. The frequency of G and A allele of Prolactin gene (exon 3) was estimated as 0.575 and 0.425, whereas the frequencies of GG, GA and AA genotypes for Prolactin gene (exon 3) were estimated as 0.45, 0.25 and 0.30, respectively. Regression analysis inferred that, SNP (G55A) of prolactin gene (exon 3) contributed to an increase in the average test day milk yield by 321.5g which was 3.92% of the average test day milk yield. Forty Sahiwal animals (20 families) under Daughter- Dam Design were screened and it was observed that one SNP (G55A) was found in all the nine families (45%) having heterozygous (GA) genotype. Thus, it could be considered as a potential genetic marker for high milk production in Sahiwal population.
Databáze:	OpenAIRE
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